Medical Weight Loss in Philadelphia

Compare Medical Weight Loss providers in Philadelphia with transparent pricing from verified providers across Center City, Rittenhouse, the Main Line, and neighboring areas. View real prices, from real providers that fit within your budget before booking an appointment.

Enter a 5-digit ZIP code to sort providers by distance.

Medical Weight Loss in Philadelphia typically costs $330-$1,320 per treatment ($330-$495 per month).

Top Medical Weight Loss providers in Philadelphia

Yardley · 19067

Bella Body Medical Spa

4.9 · 459 Google reviews
734 Stony Hill Rd 2nd Floor, Yardley, PA, 19067
$330-$495/month
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King of Prussia · 19406

Lux Skin & Lasers Med Spa by John Lee, MD

5.0 · 347 Google reviews
731 W Dekalb Pike, King of Prussia, PA, 19406
$330-$495/month
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Northern Liberties · 19123

Studio N

4.9 · 264 Google reviews
1040 N American St Unit 1101, Philadelphia, PA, 19123
$330-$495/month
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Philadelphia · 19122

Nirvana Wellness Med Spa & Beauty

4.8 · 254 Google reviews
Billy Penn Studios, 1516 N 5th St Unit 116, Philadelphia, PA, 19122
$330-$495/month
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Glen Mills · 19342

Michelle Esthetics

5.0 · 194 Google reviews
43 Regency Plaza, Glen Mills, PA, 19342
$330-$495/month
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Old City · 19106

Yofi MedSpa

5.0 · 171 Google reviews
124 Chestnut St, Philadelphia, PA, 19106
$330-$495/month
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Dresher · 19025

La Chelè Medical Aesthetics Upper Dublin

5.0 · 139 Google reviews
225 Dryden Rd, Dresher, PA, 19025
$330-$495/month
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Media · 19063

Natalie Rose • Beauty • Med Spa • Wellness

4.9 · 111 Google reviews
605 E Baltimore Ave, Media, PA, 19063
$330-$495/month
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Manayunk · 19127

Citrine Glow Medispa

5.0 · 74 Google reviews
4430 Main St 2nd Floor, Philadelphia, PA, 19127
$330-$495/month
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This page lists 9 Medical Weight Loss providers across Yardley, King of Prussia, Northern Liberties, Glen Mills and nearby areas. All of them have public Google ratings shown above.

Pricing shown is estimated based on Philadelphia regional averages unless marked "Provider verified." Ratings and review counts are public Google ratings. Always confirm pricing directly with the provider.

What is Medical Weight Loss?

Medical weight loss uses prescription GLP-1 or GLP-1/GIP medications — primarily semaglutide (Wegovy) and tirzepatide (Zepbound), the two FDA-approved formulations for weight loss — to regulate appetite, slow digestion, and produce clinically significant weight loss. Most patients lose 15% to 20% of body weight over 6 to 12 months.

Treatment involves weekly subcutaneous injections at home. Initial consultation typically includes bloodwork, BMI calculation, and a review of your goals and medical history. Dose escalation is gradual — most patients start at a low dose and increase every 4 weeks to minimize side effects (nausea, fatigue, constipation).

Medical weight loss is priced monthly, and most providers bundle the medication, injection supplies, provider check-ins, and labs into the monthly fee. Compounded versions of semaglutide and tirzepatide are often significantly cheaper than brand-name Wegovy or Zepbound.

How much does Medical Weight Loss cost in Philadelphia?

Medical weight loss in Philadelphia typically costs $330 to $1,320 per month depending on the drug, brand vs compounded formulation, and whether labs are included. Brand-name Wegovy and Zepbound cost more than compounded alternatives.

Compounded semaglutide
Monthly, includes medication
$330-550/month
Compounded tirzepatide
Monthly, includes medication
$440-770/month
Brand Wegovy
Monthly, without insurance
$990-1,320/month
Brand Zepbound
Monthly, without insurance
$1,100-1,320/month

Last updated July 2026. Estimates reflect Philadelphia regional averages and Get Clear Beauty provider data — read how we estimate prices.

What to ask your provider

Frequently asked questions

How much does medical weight loss cost in Philadelphia?
Medical weight loss in Philadelphia typically costs $300 to $1,200 per month. Compounded semaglutide runs $300 to $500/month, compounded tirzepatide $400 to $700/month. Brand Wegovy and Zepbound run $900 to $1,200/month without insurance.
Semaglutide vs tirzepatide — which should I choose?
Both work by regulating appetite and slowing digestion. Tirzepatide (Zepbound) tends to produce slightly more weight loss in clinical trials (20-22% vs 15-17% for semaglutide). Tirzepatide can also have milder GI side effects for some patients. Your provider should recommend based on your medical history, budget, and goals.
Can I get Ozempic for weight loss in Philadelphia?
Ozempic is FDA-approved only for type 2 diabetes. The same molecule, semaglutide, is FDA-approved for weight loss under the brand name Wegovy. Compounded semaglutide is also available through some providers. Your provider will recommend the appropriate prescription based on FDA approvals, your medical history, and your goals.
What about Mounjaro for weight loss?
Mounjaro is FDA-approved only for type 2 diabetes. The same molecule, tirzepatide, is FDA-approved for weight loss under the brand name Zepbound. Compounded tirzepatide is also available through some providers.
Is compounded semaglutide safe?
Compounded semaglutide is made by licensed compounding pharmacies when the brand-name drug is in shortage. It can be safe when obtained from reputable, state-licensed pharmacies. Avoid online marketplaces with vague sourcing. Always ask your provider where their pharmacy sources compounded drugs.
What are the side effects of GLP-1 medications?
Common side effects include nausea, fatigue, constipation, and decreased appetite — usually strongest at the start and after each dose increase. Serious but rare side effects include pancreatitis and gallbladder issues. Your provider should monitor you closely with regular check-ins and labs.
How long do I stay on GLP-1 medications?
Most patients stay on medication for 6 to 12 months to reach their goal weight, then transition to a maintenance dose. Stopping entirely often leads to weight regain unless significant lifestyle changes are in place. Plan this with your provider — medical weight loss is usually long-term.
Where can I find medical weight loss providers in Philadelphia?
GLP-1 prescribers in Philadelphia range from med spas and concierge clinics to telehealth practices. Philadelphia offers a competitive mix of established practices and boutique studios, keeping prices close to the national median. Use the provider list above to compare local practices across Center City, Rittenhouse, the Main Line, and neighboring areas that offer semaglutide or tirzepatide programs.
Where can I find Medical Weight Loss near me?
Get Clear Beauty lists verified Medical Weight Loss providers with prices posted up front across Center City, Rittenhouse, the Main Line, and neighboring areas. Search by ZIP code to find the closest providers to your location and compare prices before you book.
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