Polynucleotides in Chicago

Compare Polynucleotides providers in Chicago with transparent pricing from verified providers across the Loop, River North, Lincoln Park, and neighboring areas. View real prices, from real providers that fit within your budget before booking an appointment.

Enter a 5-digit ZIP code to sort providers by distance.

Polynucleotides in Chicago typically costs $600-$1,080 per treatment ($600-$1,080 per session).

Top Polynucleotides providers in Chicago

South Loop · 60605

Advanced Dermatology & Aesthetic Medicine

4.6 · 210 Google reviews
850 S Wabash Ave Suite 200, Chicago, IL, 60605
$600-$1,080/session
Estimated pricing
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River North · 60654

Aesthetic Beauty Lounge, Inc

4.9 · 91 Google reviews
20 W Ontario St #300, Chicago, IL, 60654
$600-$1,080/session
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West Loop · 60607

Aesthetica by Dr. Adam

4.9 · 230 Google reviews
924 W Madison St, Chicago, IL, 60607
$600-$1,080/session
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Streeterville · 60611

AirSculpt - Chicago

4.8 · 364 Google reviews
60 E Delaware Pl Suite 1400, Chicago, IL, 60611
$600-$1,080/session
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Northbrook · 60062

Akhil Seth, M.D.

5.0 · 260 Google reviews
501 Skokie Blvd Suite 250, Northbrook, IL, 60062
$600-$1,080/session
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Tinley Park · 60477

Allure Laser & Med Spa

4.6 · 57 Google reviews
7151 183rd St, Tinley Park, IL, 60477
$600-$1,080/session
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Logan Square · 60647

Ally B Aesthetics

5.0 · 34 Google reviews
1757 N Kimball Ave #209, Chicago, IL, 60647
$600-$1,080/session
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Streeterville · 60611

Amir H. Dorafshar, MD

5.0 · 4 Google reviews
Evolve Your Life, 60 E Delaware Pl #1430, Chicago, IL, 60611
$600-$1,080/session
Estimated pricing
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Near West Side · 60612

Amir H. Dorafshar, MD

5.0 · 26 Google reviews
1725 W Harrison St Suite 425, Chicago, IL, 60612
$600-$1,080/session
Estimated pricing
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This page lists 9 Polynucleotides providers across South Loop, River North, West Loop, Streeterville and nearby areas. All of them have public Google ratings shown above.

Pricing shown is estimated based on Chicago regional averages unless marked "Provider verified." Ratings and review counts are public Google ratings.
Always confirm pricing directly with the provider.

What is a Polynucleotides?

Polynucleotides are injectable skin boosters made from purified DNA fragments (often salmon-derived) that stimulate the skin's own repair processes — boosting hydration, elasticity, and collagen. Unlike filler, they do not add volume; they improve skin quality from within.

They are popular for under-eye crepiness and dark circles, overall skin laxity, and dull or thinning skin. A course of 2 to 3 sessions spaced a few weeks apart is standard, with results building gradually and lasting several months.

Pricing is per session, and a series is recommended for meaningful improvement.

How much does a Polynucleotides cost in Chicago?

Polynucleotide skin boosters in Chicago typically cost $600 to $1,080 per session, with most patients needing a course of 2 to 3 sessions.

Single session
Face or under-eyes
$600-1,080
Under-eye treatment
Per session
$600-960
Course of 3
Standard protocol
$1,680-3,000
Maintenance session
Every 6-9 months
$600-960

Last updated June 2026. Estimates reflect Chicago regional averages and Get Clear Beauty provider data — read how we estimate prices.

What to ask your provider

Frequently asked questions

How much do polynucleotides cost in Chicago?
Polynucleotide treatments in Chicago typically cost $600 to $1,080 per session. A course of 2 to 3 sessions is standard, so factor the full series into your budget.
What are polynucleotides used for?
They are skin boosters that improve hydration, elasticity, and collagen. They are especially popular for crepey under-eye skin, dark circles, and overall skin quality. They do not add volume like filler does.
Are polynucleotides the same as filler?
No. Filler adds volume to fill hollows or lines. Polynucleotides improve the skin's quality and resilience from within without volumizing, which makes them useful for delicate areas like under the eyes.
How long do polynucleotide results last?
Results build over the course of treatment and typically last several months. Many patients maintain the effect with a session every 6 to 9 months.
Where can I find Polynucleotides near me?
Get Clear Beauty lists verified Polynucleotides providers with prices posted up front across the Loop, River North, Lincoln Park, and neighboring areas. Search by ZIP code to find the closest providers to your location and compare prices before you book.
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