Washington Square West · 19107
View profile
4Ever Young Med Spa & Wellness Center - Philadelphia
1216 Walnut St, Philadelphia, PA, 19107
$550-$990/session
Estimated pricing
Polynucleotides in Philadelphia
Compare Polynucleotides providers in Philadelphia with transparent pricing from verified providers across Center City, Rittenhouse, the Main Line, and neighboring areas. View real prices, from real providers that fit within your budget before booking an appointment.
Enter a 5-digit ZIP code to sort providers by distance.
Polynucleotides in Philadelphia typically costs $550-$990 per treatment ($550-$990 per session).
Top Polynucleotides providers in Philadelphia
Glen Mills · 19342
View profile
Adrienne Rencic, MD
30 Lacrue Ave #104, Glen Mills, PA, 19342
$550-$990/session
Estimated pricing
Media · 19063
View profile
Aesthetic Dermatology Associates, PC
176 S New Middletown Rd #203, Media, PA, 19063
$550-$990/session
Estimated pricing
Paoli · 19301
View profile
Aesthetic Dermatology Associates, PC
4 Industrial Blvd STE 200, Paoli, PA, 19301
$550-$990/session
Estimated pricing
Old City · 19106
View profile
Ari Blanc Medical Spa
7 N Christopher Columbus Blvd Suite 302, Philadelphia, PA, 19106
$550-$990/session
Estimated pricing
Bala Cynwyd · 19004
View profile
Bala Dermatology
1 Bala Plaza #620, Bala Cynwyd, PA, 19004
$550-$990/session
Estimated pricing
Yardley · 19067
View profile
Bella Body Medical Spa
734 Stony Hill Rd 2nd Floor, Yardley, PA, 19067
$550-$990/session
Estimated pricing
Newtown Square · 19073
View profile
Benstock Dermatology
3501 West Chester Pike # 202, Newtown Square, PA, 19073
$550-$990/session
Estimated pricing
Blue Bell · 19422
View profile
Best Impression Med Spa
1050 Dekalb Pike, Blue Bell, PA, 19422
$550-$990/session
Estimated pricing
This page lists 9 Polynucleotides providers across Washington Square West, Glen Mills, Media, Paoli and nearby areas. All of them have public Google ratings shown above.
Pricing shown is estimated based on Philadelphia regional averages unless marked "Provider verified." Ratings and review counts are public Google ratings.
Always confirm pricing directly with the provider.
What is a Polynucleotides?
Polynucleotides are injectable skin boosters made from purified DNA fragments (often salmon-derived) that stimulate the skin's own repair processes — boosting hydration, elasticity, and collagen. Unlike filler, they do not add volume; they improve skin quality from within.
They are popular for under-eye crepiness and dark circles, overall skin laxity, and dull or thinning skin. A course of 2 to 3 sessions spaced a few weeks apart is standard, with results building gradually and lasting several months.
Pricing is per session, and a series is recommended for meaningful improvement.
How much does a Polynucleotides cost in Philadelphia?
Polynucleotide skin boosters in Philadelphia typically cost $550 to $990 per session, with most patients needing a course of 2 to 3 sessions.
Single session
Face or under-eyes
$550-990
Under-eye treatment
Per session
$550-880
Course of 3
Standard protocol
$1,540-2,750
Maintenance session
Every 6-9 months
$550-880
Last updated June 2026. Estimates reflect Philadelphia regional averages and Get Clear Beauty provider data — read how we estimate prices.
What to ask your provider
- Are polynucleotides the right choice for my skin concern?
- How many sessions do you recommend?
- How are they different from filler for my under-eyes?
- When will I see results and how long do they last?
- What product or brand do you use?
- What is the per-session and full-course cost?
Frequently asked questions
How much do polynucleotides cost in Philadelphia?
Polynucleotide treatments in Philadelphia typically cost $550 to $990 per session. A course of 2 to 3 sessions is standard, so factor the full series into your budget.
What are polynucleotides used for?
They are skin boosters that improve hydration, elasticity, and collagen. They are especially popular for crepey under-eye skin, dark circles, and overall skin quality. They do not add volume like filler does.
Are polynucleotides the same as filler?
No. Filler adds volume to fill hollows or lines. Polynucleotides improve the skin's quality and resilience from within without volumizing, which makes them useful for delicate areas like under the eyes.
How long do polynucleotide results last?
Results build over the course of treatment and typically last several months. Many patients maintain the effect with a session every 6 to 9 months.
Where can I find Polynucleotides near me?
Get Clear Beauty lists verified Polynucleotides providers with prices posted up front across Center City, Rittenhouse, the Main Line, and neighboring areas. Search by ZIP code to find the closest providers to your location and compare prices before you book.
Not sure Polynucleotides is right for you?
Take our treatment quiz →