Polynucleotides in San Francisco

Compare Polynucleotides providers in San Francisco with transparent pricing from verified providers across SF proper, Oakland, the Peninsula, and neighboring areas. View real prices, from real providers that fit within your budget before booking an appointment.

Enter a 5-digit ZIP code to sort providers by distance.

Polynucleotides in San Francisco typically costs $700-$1,260 per treatment ($700-$1,260 per session).

Top Polynucleotides providers in San Francisco

Inner Richmond · 94118

Aaron Chen, DO

3838 California St RM 610, San Francisco, CA, 94118
$700-$1,260/session
Estimated pricing
View profile
Orinda · 94563

Adrianna J. Browne, M.D.

4.7 · 77 Google reviews
8 Cam Encinas #115, Orinda, CA, 94563
$700-$1,260/session
Estimated pricing
View profile
San Rafael · 94901

Advanced Medical & Surgical Dermatology

5.0 · 22 Google reviews
712 D St D, San Rafael, CA, 94901
$700-$1,260/session
Estimated pricing
View profile
Mill Valley · 94941

Aesthetic Dermatology and Skin Cancer: Stefan Lowenstein, M.D.

4.9 · 340 Google reviews
535 Miller Ave, Mill Valley, CA, 94941
$700-$1,260/session
Estimated pricing
View profile
Walnut Creek · 94596

Afshin Parhiscar, MD

4.8 · 42 Google reviews
1844 San Miguel Dr #109, Walnut Creek, CA, 94596
$700-$1,260/session
Estimated pricing
View profile
Mission District · 94110

Aileen Chang

1001 Potrero Ave, San Francisco, CA, 94110
$700-$1,260/session
Estimated pricing
View profile
San Francisco · 94143

Aileen Chang

3.0 · 2 Google reviews
505 Parnassus Ave, San Francisco, CA, 94143
$700-$1,260/session
Estimated pricing
View profile
Redwood City · 94063

Albert Sean Chiou, MD, MBA

450 Broadway Pavilion B 4th Floor, Redwood City, CA, 94063
$700-$1,260/session
Estimated pricing
View profile
Nob Hill · 94109

Albert W. Chow, M.D.

5.0 · 15 Google reviews
1 Daniel Burnham Ct ste 368c, San Francisco, CA, 94109
$700-$1,260/session
Estimated pricing
View profile

This page lists 9 Polynucleotides providers across Inner Richmond, Orinda, San Rafael, Mill Valley and nearby areas. 6 of them have public Google ratings shown above.

Pricing shown is estimated based on San Francisco regional averages unless marked "Provider verified." Ratings and review counts are public Google ratings.
Always confirm pricing directly with the provider.

What is a Polynucleotides?

Polynucleotides are injectable skin boosters made from purified DNA fragments (often salmon-derived) that stimulate the skin's own repair processes — boosting hydration, elasticity, and collagen. Unlike filler, they do not add volume; they improve skin quality from within.

They are popular for under-eye crepiness and dark circles, overall skin laxity, and dull or thinning skin. A course of 2 to 3 sessions spaced a few weeks apart is standard, with results building gradually and lasting several months.

Pricing is per session, and a series is recommended for meaningful improvement.

How much does a Polynucleotides cost in San Francisco?

Polynucleotide skin boosters in San Francisco typically cost $700 to $1,260 per session, with most patients needing a course of 2 to 3 sessions.

Single session
Face or under-eyes
$700-1,260
Under-eye treatment
Per session
$700-1,120
Course of 3
Standard protocol
$1,960-3,500
Maintenance session
Every 6-9 months
$700-1,120

Last updated June 2026. Estimates reflect San Francisco regional averages and Get Clear Beauty provider data — read how we estimate prices.

What to ask your provider

Frequently asked questions

How much do polynucleotides cost in San Francisco?
Polynucleotide treatments in San Francisco typically cost $700 to $1,260 per session. A course of 2 to 3 sessions is standard, so factor the full series into your budget.
What are polynucleotides used for?
They are skin boosters that improve hydration, elasticity, and collagen. They are especially popular for crepey under-eye skin, dark circles, and overall skin quality. They do not add volume like filler does.
Are polynucleotides the same as filler?
No. Filler adds volume to fill hollows or lines. Polynucleotides improve the skin's quality and resilience from within without volumizing, which makes them useful for delicate areas like under the eyes.
How long do polynucleotide results last?
Results build over the course of treatment and typically last several months. Many patients maintain the effect with a session every 6 to 9 months.
Where can I find Polynucleotides near me?
Get Clear Beauty lists verified Polynucleotides providers with prices posted up front across SF proper, Oakland, the Peninsula, and neighboring areas. Search by ZIP code to find the closest providers to your location and compare prices before you book.
Not sure Polynucleotides is right for you?
Take our treatment quiz →