Xeomin Treatment Guide

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What is Xeomin?

Xeomin (incobotulinumtoxinA) is an FDA-approved neuromodulator that works like Botox and Dysport to temporarily relax facial muscles and soften wrinkles. It is often called "naked Botox" because it is formulated without the complexing proteins found in Botox — just pure botulinum toxin type A.

This stripped-down formulation means Xeomin does not require refrigeration before opening and may be less likely to cause antibody formation over time (though the clinical significance of this is debated). Xeomin units are 1:1 equivalent to Botox units. Results appear in 3 to 5 days and last 3 to 4 months.

How much does Xeomin cost?

Xeomin nationally typically costs $10–$15 per unit, with a typical full treatment totaling $300–$700. Xeomin units are equivalent to Botox units (1:1), making price comparisons straightforward.

Forehead lines
10-20 units
$100-300
Frown lines (glabella)
15-30 units
$150-450
Crow's feet
8-16 units per side
$160-480
Full upper face
Typical treatment
$300-$700

Last updated June 2026. Estimates reflect national averages and Get Clear Beauty provider data — read how we estimate prices.

What to ask your provider

Frequently asked questions

How much does Xeomin cost?
Xeomin across the US typically runs $10–$15 per unit, with a full treatment totaling $300–$700. Because Xeomin units are 1:1 with Botox units, per-unit price comparisons are straightforward. the US pricing is broadly in line with national averages.
What is the difference between Xeomin and Botox?
Both use botulinum toxin type A and produce the same muscle-relaxing effect. Xeomin contains only the pure toxin without complexing proteins, while Botox includes them. Units are equivalent. In practice, most patients cannot distinguish the results.
Does Xeomin work for patients who have become resistant to Botox?
Antibody resistance to Botox is theoretically possible with long-term use, though rare. Some providers switch patients to Xeomin when they feel Botox is losing effectiveness. The evidence is limited, but trying an alternative neuromodulator is a reasonable next step.
How long does Xeomin last?
Xeomin typically lasts 3 to 4 months, similar to Botox and Dysport.
Where can I find Xeomin near me?
Get Clear Beauty lists verified Xeomin providers with prices posted up front across major US cities. Search by ZIP code to find the closest providers to your location and compare prices before you book.